a lot of the big issues with frame times these days are either shader compilation or traversal stutters, both of which happen regardless of your monitor is driving. In my experience, if a game does not suffer from either of these issues, using VRR you can usually mostly smooth out smaller frametime variations fairly well. And push comes to shove, there's always tools like RTSS, Special K and the like.
Been using a 240 Hz monitor since start of this year, usually hovering above 120 FPS in games, and it's a really noticable bump in motion clarity over 60, especially on an OLED. Going back to 60 FPS on an LCD over the summer just felt so blurry. Like I kept checked that motion blur was not activated in games, but had to accept that what I was seeing was just how that monitor works.